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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENPP2 All Species: 27.27
Human Site: T851 Identified Species: 60
UniProt: Q13822 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13822 NP_001035181.1 863 98994 T851 R S Y P E I L T L K T Y L H T
Chimpanzee Pan troglodytes XP_001143143 888 101936 T876 R S Y P E I L T L K T Y L H T
Rhesus Macaque Macaca mulatta XP_001093656 982 112340 T970 R S Y P E I L T L K T Y L H T
Dog Lupus familis XP_861274 859 98531 T847 R S Y P E I L T L K T Y L H T
Cat Felis silvestris
Mouse Mus musculus Q9R1E6 862 98867 T850 R S Y S E I L T L K T Y L H T
Rat Rattus norvegicus Q64610 887 101558 T875 R S Y S E I L T L K T Y L H T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505967 868 99060 K856 W P V S E V L K L K T F L P T
Chicken Gallus gallus XP_418466 915 104916 S903 R S Y T E I L S L K T Y L H T
Frog Xenopus laevis NP_001080526 874 99632 L863 S Y T E I L S L K T Y L H T Y
Zebra Danio Brachydanio rerio NP_956897 850 97175 L839 T Y E E I L A L K T Y L H T Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90754 829 93146 T818 A L S Q N Q N T I I R R K I S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.5 86.8 95.3 N.A. 94 91.3 N.A. 45.3 79.3 73.8 66 N.A. N.A. N.A. 24.4 N.A.
Protein Similarity: 100 97 87.3 97.6 N.A. 97.2 94.5 N.A. 62.7 86.9 86.5 82.2 N.A. N.A. N.A. 41.3 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 46.6 86.6 0 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 60 93.3 6.6 6.6 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 19 73 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 19 64 0 % H
% Ile: 0 0 0 0 19 64 0 0 10 10 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 10 19 73 0 0 10 0 0 % K
% Leu: 0 10 0 0 0 19 73 19 73 0 0 19 73 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 37 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 64 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % R
% Ser: 10 64 10 28 0 0 10 10 0 0 0 0 0 0 10 % S
% Thr: 10 0 10 10 0 0 0 64 0 19 73 0 0 19 73 % T
% Val: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 19 64 0 0 0 0 0 0 0 19 64 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _